dr. J.F.C. Tomee | Allergoloog

Studie & opleiding

• 1984-1990 Studie Medische Biologie Rijksuniversiteit Groningen (cum laude)
• 1987-1989 Research stages op het NKI-AVL Amsterdam en RIVM Bilthoven
• 1990-1995 Wetenschappelijk onderzoeker Rijksuniversiteit Groningen, afdelingen Fysiologische Chemie en Allergologie
• 1995-1999 Promotieonderzoek Rijksuniversiteit Groningen
• 1996-1997 Wetenschappelijk onderzoeker University of Southampton
• 1997-2002 Studie Geneeskunde Rijksuniversiteit Groningen
• 1999-2003 Post-doc onderzoeker UMCG afdeling Allergologie en Longziekten
• 2003-2005 Arts interne geneeskunde, longziekten, cardiologie, spoedeisende hulp, Martini Ziekenhuis Groningen
• 2005-2010 Opleiding Interne Geneeskunde UMCG
• 2005-2008 Opleidingsstages Interne Geneeskunde ZGT Almelo
• 2008-2010 Opleidingsstages Interne -Allergologie UMCG

Onderzoek & publicaties

• Papillary carcinoma in struma ovarii: an unusual presentation.
  Tomee JF, van der Heijden PF, van den Hout JH, Brinkhuis M, Veneman TF.
  Neth J Med. 2008 Jun;66(6):248-51.
• Defense mechanisms of the airways against Aspergillus fumigatus: role in invasive aspergillosis.Kauffman HF, Tomee JF.Chem Immunol. 2002;81:94-113.
• Pulmonary aspergillosis. Tomee JF, van der Werf TS. Neth J Med. 2001 Nov;59(5):244-58.
• Protease-dependent activation of epithelial cells by fungal allergens leads to morphologic changes and cytokine production. Kauffman HF, Tomee JF, van de Riet MA, Timmerman AJ, Borger P. J Allergy Clin Immunol. 2000 Jun;105(6 Pt 1):1185-93.
• Putative virulence factors of Aspergillus fumigatus. Tomee JF, Kauffman HF. Clin Exp Allergy. 2000 Apr;30(4):476-84.
• Proteases from Aspergillus fumigatus induce interleukin (IL)-6 and IL-8 production in airway epithelial cell lines by transcriptional mechanisms. Borger P, Koëter GH, Timmerman JA, Vellenga E, Tomee JF, Kauffman HF. J Infect Dis. 1999 Oct;180(4):1267-74.
• Interactions between inhalant allergen extracts and airway epithelial cells: effect on cytokine production and cell detachment. Tomee JF, van Weissenbruch R, de Monchy JG, Kauffman HF. J Allergy Clin Immunol. 1998 Jul;102(1):75-85.
• Secretory leukoprotease inhibitor: a native antimicrobial protein presenting a new therapeutic option? Tomee JF, Koëter GH, Hiemstra PS, Kauffman HF. Thorax. 1998 Feb;53(2):114-6. Review.
• Antileukoprotease: an endogenous protein in the innate mucosal defense against fungi. Tomee JF, Hiemstra PS, Heinzel-Wieland R, Kauffman HF. J Infect Dis. 1997 Sep;176(3):740-7.
• Proteases from Aspergillus fumigatus induce release of proinflammatory cytokines and cell detachment in airway epithelial cell lines. Tomee JF, Wierenga AT, Hiemstra PS, Kauffman HK. J Infect Dis. 1997 Jul;176(1):300-3.
• Serodiagnosis and monitoring of Aspergillus infections after lung transplantation. Tomee JF, Mannes GP, van der Bij W, van der Werf TS, de Boer WJ, Koëter GH, Kauffman HF. Ann Intern Med. 1996 Aug 1;125(3):197-201.
• Specific IgG4 responses during chronic and transient antigen exposure in aspergillosis. Tomee JF, Dubois AE, Koëter GH, Beaumont F, van der Werf TS, Kauffman HF. Am J Respir Crit Care Med. 1996 Jun;153(6 Pt 1):1952-7.
• Liposomes as an immunoadjuvant system for stimulation of mucosal and systemic antibody responses against inactivated measles virus administered intranasally to mice. de Haan A, Tomee JF, Huchshorn JP, Wilschut J. Vaccine. 1995 Oct;13(14):1320-4.

Review of fungus-induced asthmatic reactions.
Kauffman HF, Tomee JF, van der Werf TS, de Monchy JG, Koëter GK.
Am J Respir Crit Care Med. 1995 Jun;151(6):2109-15; 

Serologic monitoring of disease and treatment in a patient with pulmonary aspergilloma.
Tomee JF, van der Werf TS, Latge JP, Koeter GH, Dubois AE, Kauffman HF.
Am J Respir Crit Care Med. 1995 Jan;151(1):199-204.

Immunologic significance of a collagen-derived culture filtrate containing proteolytic activity in Aspergillus-related diseases.
Tomee JF, Kauffman HF, Klimp AH, de Monchy JG, Köeter GH, Dubois AE.
J Allergy Clin Immunol. 1994 Apr;93(4):768-78.

Induction of feline leukaemia virus-neutralizing antibodies by immunization with synthetic peptides derived from the FeLV env gene.
Weijer K, Pfauth A, van Herwijnen R, Jarrett O, Meloen RH, Tomee C, Osterhaus AD.
Vaccine. 1993;11(9):946-56.

 

Lidmaatschappen

• NVVA, Nederlandse Vereniging voor Allergologie
• EAACI, European Academy of Allergy and Clinical Immunology
• NIV, Nederlands Internisten Vereniging
• Lid dagelijks bestuur Nederlandse Vereniging voor Allergologie

 

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